Workshop A – Leveraging Biocatalysis & Enzyme Engineering: Rethinking mRNA Process Development for Scalable, Efficient & High-Quality Production
Time: 9:00 am
day: Pre-Conference Workshop Day
Details:
This interactive workshop delves into the role of biocatalysis and enzyme engineering in mRNA process development and manufacturing. Discover how precision enzyme design and optimization can overcome production and scaling bottlenecks to deliver high-quality therapeutics and vaccines for meeting global demands and regulatory expectations efficiently. By bridging theory and real-world applications, this session will provide expert insights and actionable strategies to streamline workflows, reduce costs, and improve product quality.
- How can biocatalytic approaches be leveraged to streamline mRNA production for improved reaction efficiency and reduction of cost in process development?
- How to optimise enzymatic processes in IVT to maximise performance at room temperature, yield and scalability without compromising mRNA integrity?
- How to leverage high-throughput screening methods to rapidly identify enzyme variants and mutants for improved catalytic efficiency in IVT?
- How can enzyme selection and engineering be tailored to align mRNA production with evolving EU regulatory requirements for clinical readiness?