Aleš Štrancar

Aleš Štrancar

Company: Sartorius BIA Separations

Job title: Executive Managing Director


Development of In-Process Analytics to Enable Robust mRNA Manufacturing 10:30 am

Typical mRNA production process involves four key steps: 1) plasmid DNA (pDNA) expression in E.coli, linearisation and pDNA purification, 2) in-vitro transcription (IVT) reaction, 3) mRNA purification and 4) mRNA encapsulation In this paper a chromatographic toolbox and optimised IVT synthesis, including instant in-process analytics, will be presented This well controlled and high IVT yield…Read more

day: Conference Day One

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