Antonio Grilo
Associate Director, External Manufacturing MSD
Seminars
Wednesday 20th May 2026
Roundtable Discussion: Rethinking mRNA Drug Substance Outsourcing: Designing Quality, Control & Scalability into External Manufacturing
9:30 am
- Positioning outsourcing as a quality and control decision, examining how choices around DNA templates, enzymes, buffers, consumables, and equipment directly shape drug substance robustness and downstream risk
- Defining fit-for-purpose outsourcing strategies across the lifecycle, from early development through scale-up and commercial readiness, and how expectations of external partners must evolve accordingly
- Critically assessing vendor capability beyond capacity, including process understanding, data transparency, change control, and the ability to support comparability and regulatory scrutiny
