Regina Bleul
Head of Nanomedicine Group Fraunhofer ICT-IMM
Seminars
Thursday 21st May 2026
Building Modular & Automated Formulation Platforms for Scalable mRNA Drug Product Development
11:30 am
- Designing modular formulation and downstream processing units, including microfluidic mixing and tangential flow filtration as an inline purification module, to support adaptable, continuous mRNA drug product workflows
- Embedding process analytical technologies (PAT) directly into formulation operations, leveraging inline DLS as a dedicated PAT module alongside nano-analytics to enable real-time monitoring and control of LNP quality attributes
- Integrating automation and AI-driven optimisation across formulation workflows, accelerating development while maintaining flexibility across payloads, materials, and delivery system architectures
