Suzanne Saffie-Siebert
Founder & Chief Executive Officer Sisaf Ltd
Seminars
Thursday 21st May 2026
Overcoming RNA Delivery Constraints with Silicon-Stabilised Hybrid Lipid Nanoparticles
12:30 pm
- Introducing silicon-stabilised hybrid lipid nanoparticles (sshLNP) as a next-generation RNA delivery platform, combining organic lipid systems with bioabsorbable inorganic silicon to overcome stability and safety limitations of conventional LNPs
- Demonstrating how sshLNP architecture improves RNA stability, transfection efficiency, and tolerability, enabling more reliable delivery across challenging genetic targets and rare disease applications
- Translating delivery innovation into scalable therapeutic development, outlining how integrated bio-analytical capabilities and platform scalability, support rapid progression to clinic
