Highlighting a Combined Mechanistic Modelling & Machine Learning Approach to the IVT Reaction to Improve mRNA Yield & Process Controls to Aid Downstream Purification
Time: 9:30 am
day: Day One
Details:
- Learning how a hybrid modeling approach improve process controls and understanding
- Utilising digital twin modelling as key ingredient to a Quality by Design manufacturing approach
- Demonstrating how model-driven optimisation leads to a higher mRNA purity to facilitate downstream purification