Workshop B: Overcoming the mRNA Sequence Design Problem to Generate RNA Therapeutics with High Manufacturing Efficiency & Biological Activity
Time: 11:00 am
day: Pre-Conference Day
Details:
Optimising mRNA sequence design is crucial to establish structure and stability of the final mRNA drug substance, which must balance cost and efficacy. Further hurdles include weighing up the factors of an ideal mRNA construct with the importance of manufacturability and the costs of 5’ capping. Join this workshop to explore how the latest advancements will enable the design of stable and efficacious mRNA constructs to facilitate manufacturability of next generation therapeutics.
Join this workshop to learn:
- How to secure the optimal mRNA construct tools to maximise efficacy and stability?
- How to balance efficacy and stability of an mRNA construct with its manufacturability to deliver on production and reduce costs?
- Understand which computational tools can be leveraged in mRNA design to facilitate and reduce bottlenecks of downstream processes
- How to tackle bottlenecks in the 5’ capping process to boost mRNA stability?
