Transitioning From Small-Scale Development to GMP Large-Scale Production to Meet Global Demands & Increase Patient Accessibility
Time: 2:00 pm
day: Day Two
Details:
- What are the key considerations for adapting GMP facilities and equipment to handle the increased complexity and scale of mRNA production?
- How can upstream processes, including buffer preparation, raw material handling, and mixing techniques, be optimised to ensure uniformity, prevent shear stress, and minimise contamination risks?
- What strategies can improve downstream purification and sterile filtration to maintain product quality, minimise dead volumes, and meet regulatory requirements?
